Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity connected to bortezomib, a proteasome inhibitor used in the remedy of multiple myeloma. Its synthesis or research is very important for making sure the purity and security of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor in the synthesis of abiraterone acetate, a drug Employed in the treatment method of prostate cancer by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-10-1): A important compound from the synthesis of imatinib, a drug that targets unique sorts of cancer, including chronic myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers such as breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): They are intermediates in the synthesis of gemcitabine, an anti-most cancers drug. Their study is important for optimizing the creation procedure and guaranteeing high purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is utilized to take care of breast most cancers, and these intermediates are associated with its output.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Employed in the therapy of breast cancer. Several intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug helpful in treating cancers for instance ovarian, breast, and lung cancer.
3. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug used in the treatment method of colorectal most cancers and modest mobile lung most cancers.
three-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is involved with the synthesis of adamantane derivatives, that have several applications, which includes antiviral Homes.
Vildagliptin Intermediates: Utilized in the production of vildagliptin, an oral drug for style two diabetic issues that Bortezomib Acid Impurity inhibits the enzyme DPP-four to manage blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is associated with the synthesis of varied gluconic acid derivatives, that are Utilized in foodstuff, pharmaceutical, and industrial apps.
Canagliflozin Abiraterone Acetate Intermediate Intermediate 2: A precursor while in the synthesis of canagliflozin, a medication utilised to handle sort 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).